ABI Development: Refinement Algorithms and Server for Protein Docking

Sponsor: National Science Foundation (NSF)

Award Number: 1147082

PI: Sandor Vajda

Co-I/Co-PI: Dmytro Kozakov

公关

ClusPro already has over 4500 users and runs over 1000 jobs per month. In 2011, 164 papers used models generated using the server to study problems in biology, biochemistry, and biotechnology. The upgraded server, with its simple user interface, will be particularly useful to experimentalist with no extensive computational experience, who will be able use it for generating models of protein interactions to explain their data. Graduate students will be trained to optimally combine high performance structure prediction algorithms with experimental data from a variety of low-resolution or non-structural techniques. Docking methods are also being incorporated into undergraduate courses to teach the biophysical principles of molecular recognition.

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