Ji-Xin Cheng
Bond-selective intensity diffraction tomography
Recovering molecular information remains a grand challenge in the widely used holographic and computational imaging technologies. To address this challenge, we developed a computational mid-infrared photothermal microscope, termed Bond-selective Intensity Diffraction Tomography (BS-IDT). Based on a low-cost brightfield microscope with an add-on pulsed light source, BS-IDT recovers both infrared spectra and bond-selective 3D refractive index […]
High-content High-speed Chemical Imaging of Metabolic Reprogramming by Integration of Advanced Instrumentation and Data Science
The goal of this project is to develop two complementary stimulated Raman scattering imaging platforms that will allow high-speed, high-content, and high-sensitivity mapping of cell metabolism by synergistic integration of advanced instrumentation and data science.