Courses

The listing of a course description here does not guarantee a course’s being offered in a particular semester. Please refer to the published schedule of classes on the Student Link for confirmation a class is actually being taught and for specific course meeting dates and times.

• ENG BE 209: Principles of Molecular Cell Biology and Biotechnology
  Introduction to the molecular, physical and computational principles of cell function in the context of cutting-edge applications in bioengineering and medicine. Biological concepts include: molecular building blocks, energetics, transport, metabolism, nucleic acids, gene expression and genetics. Applications include bioenergy, synthetic biology, the human genome project, and gene circuit engineering. Labs will teach fundamental techniques of molecular biology including a multi-week module where students build and quantify bacterial gene expression system. Labs emphasize the experimental, problem solving, and analytical skills required in modern engineering and research. 4.0 cr
• ENG BE 400: Undergraduate Special Topics in Biomedical Engineering
  Specific prerequisites vary according to topic. Coverage of a specific topic in biomedical engineering at a level appropriate for advanced undergraduates. One topic covered in depth each semester offered. Subject matter varies from year to year.
• ENG BE 403: Biomedical Signals and Controls
  Signals, systems, and feedback control with an emphasis on biomedical problems, including linear time invariant systems in continuous and discrete time. Laplace and Fourier representations, transfer functions, pole-zero analysis, stability, convolution, sampling. Analytical and computational methods.
• ENG BE 404: Modern Control in Biomedical Engineering
  Mathematical analysis of feedback control systems with an emphasis on state space approaches. Linearization around an equilibrium point. Controllability, observability, and design of optimal controllers and observers. Complementary frequency-domain methods, including root locus and Nyquist analysis. Emphasis on models of biological and biomedical systems.
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• ENG BE 435: Transport Phenomena in Living Systems
  Biological systems operate at multiple length scales and all scales depend on internal and external transport of molecules, ions, fluids and heat. This course is designed to introduce the fundamentals of biological transport and to apply these fundamentals in understanding physiological processes involving fluid, mass and heat transfer. Students will learn the fundamental conservation principles and constitutive laws that govern heat, mass and momentum transport processes and systems as well as the constitutive properties that are encountered in typical biological problems. Transport is also critical to the development and proper functioning of biological and medical instruments and devices, which will also be discussed. Biomedical examples will include applications in development of the heart-lung machine, estimation of time of death in postmortem cases, burn injuries through hot water, respiratory flow in smokers lungs, etc. 4 cr
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• ENG BE 437: Nanometer Scale Processes in Living Systems
  The world at the nanometer-scale is full of dynamic phenomena that are vastly different than those encountered at the macro scale. Biological processes that are of particular contemporary interest, such as cell differentiation, are stimulated by the activity and interaction of biomolecules at the nanoscale. Thus, an understanding of the physics and engineering in such systems is a vital component toward overcoming an immense array of challenging problems in the biological and medical sciences. This course focuses on a conceptual and mechanistic understanding of technologies that permit the study of events at the nanometer scale, including scanning probe microscopes (including AFM) and optical methods such as fluorescence microscopy and related techniques (including single particle tracking, and microrheology).. 4 cr
• ENG BE 451: Directed Study in Biomedical Engineering
  Individual study of a topic in biomedical engineering not covered in a regularly scheduled course. A faculty member must agree to supervise the study before registration. Term paper and/or written examination. Variable cr.
• ENG BE 465: Biomedical Engineering Senior Project
  Selection of project and project supervisor must be approved by course instructor. Project is in an area of biomedical engineering, such as biomedical instrumentation, biosensors, tissue engineering, biological signal processing, biological modeling and simulation, clinical imaging or informational systems, etc.Projects will be conducted by teams of two or three students, and projects must include significant design experience. Research of background, planning and initial work on senior design project. Guidance in performing and presenting (in written and oral form) a technical project proposal. Skills in proposal writing, oral presentation techniques. Formal proposal must be approved by technical advisor. 2 cr
• ENG BE 466: Biomedical Engineering Senior Project
  Completion of project in an area of biomedical engineering. Expanded training in technical project presentation techniques. Includes writing of progress reports, abstracts, final reports. Course culminates with an oral presentation at annual Senior Project Conference. Written final report must be approved by the faculty. 4 cr
• ENG BE 468: Clinical Applications of Biomedical Design
  This four-credit course provides BME Seniors with an in-depth analysis of the design history of specific currently available medical devices, instruments, implants, diagnostics, and drug delivery systems. Students will recreate the clinical and device requirements, the engineering specifications, the regulatory pathways, the intellectual property, the risk management strategies, and the business models that were deployed to bring the product into clinic use.
• ENG BE 491: Biomedical Measurements I
  Laboratory course designed to accomplish four goals: 1) Develop skills for collecting and analyzing biomedical measurements, 2) Learn proper usage of electronic equipment including oscilloscope, function generator, DAQ, 3) Improve oral and written scientific communication skills through lab reports and class term project presentations, and 4) reinforce concepts presented in BE403, including Fourier Analysis, sampling theory, and filtering, with hand-on experiments. 2 cr
• ENG BE 492: Biomedical Measurements II
  Laboratory course designed to develop basic instrumentation and analysis skills for physiological and biological measurements. Emphasis will be placed on techniques involving light (spectroscopy and microscopy) and sound (ultrasound). Labs will be focused on data acquisition. Written lab reports will involve quantitative data analysis and interpretation. 2 cr
• ENG BE 500: Special Topics in Biomedical Engineering
  Coverage of a specific topic in biomedical engineering. One topic covered in depth each semester offered. Subject matter varies from year to year. 4 cr
• ENG BE 503: Numerical Methods and Modeling in Biomedical Engineering
  This course offers an advanced introduction to numerical methods for solving linear and nonlinear differential equations including ordinary differential equations and partial differential equations. Topics include numerical series, error analysis, interpolation, numerical integration and differentiation, Euler & Runge-Kutta methods, finite difference methods, finite element methods, and moving boundary problems. This course requires knowledge of multivariable calculus, linear algebra, and differential equations. Some knowledge in one computer programming language, such as MATLAB, is required. 4.0 cr
• ENG BE 504: Polymers and Soft Materials
  An introduction to soft matter for students with background in materials science, chemistry and physics. This course covers general aspects of structure, properties, and performance polymers, polymer solutions and gels. Emphasis is on chain behavior, local chemical interactions and mechanical behavior across multiple size scales. Topics include methods and kinetics of material synthesis, formation assembly, and phase behavior; models of polymer mechanical behavior; techniques for characterizing the structure, phase and dynamics of soft materials; application of soft materials in biotechnology and nanotechnology. Meets with ENG ME 504, ENG MS 504 and PY 744; students may not receive credit for both. 4 cr
• ENG BE 505: Molecular Bioengineering I
  Provides engineering perspectives on the building blocks of living cells and materials for biotechnology. Focuses on origins and synthesis in life and the laboratory, including biological pathways for sythesis of DNA, RNA and proteins; transduction, transmission, storage and retrieval of biological informatin by macromoleclues; polyerase chain reaction, restriction enzymes, DNA sequencing; energetics of protein folding and trafficking; mechanisms of enzymatic catalysts and receptor-ligand binding; cooperative proteins, multi-protein complexes and control of metabolic pathways; generation, storage, transmission and release of biomolecular energy; and methods for study and manipulation of molecules which will include isolation, purification, detection, chemical characterization, imaging and visualization of structure. 4 cr
• ENG BE 508: Quantitative Studies of the Respiratory and Cardiovascular Systems
  The quantitative physiological aspects of the respiratory and cardiovascular systems are studied. Classical models of these systems are considered including lumped element models, branching tree structures, and distributed parameter models to predict wave propagation in compliant walled tubes filled with compressible or incompressible fluids. Extensive computer models are developed to simulate the behavior of these systems in the frequency and time domains. Includes lab. 4 cr

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