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- ENG BE 200: Introduction to Probability
An introductory course designed for sophomore engineering students that introduces the fundamentals of probability and statistics without the use of transforms. Coverage includes descriptive statistics, basics of probability theory, multiple random variables, expectation, Markov chains, and statistical testing. Computer simulations of probabilistic systems are included. Examples are taken from engineering systems. This course cannot be taken for credit in addition to ENG EC 381. 2.0 cr - ENG BE 209: Principles of Molecular Cell Biology and Biotechnology
Introduction to the molecular, physical and computational principles of cell function in the context of cutting-edge applications in bioengineering and medicine. Biological concepts include: molecular building blocks, energetics, transport, metabolism, nucleic acids, gene expression and genetics. Applications include bioenergy, synthetic biology, the human genome project, and gene circuit engineering. Labs will teach fundamental techniques of molecular biology including a multi-week module where students build and quantify bacterial gene expression system. Labs emphasize the experimental, problem solving, and analytical skills required in modern engineering and research. 4.0 cr - ENG BE 401: Signals and Systems in Biomedical Engineering
Signals and systems with an emphasis on biomedical problems, including linear time invariant systems, Laplace and Fourier representations, transfer functions, pole-zero analysis, and convolution. Introduction to filtering, modulation, windowing, and sampling. Cannot be taken for credit in addition to ENG SC 401. 4 cr - ENG BE 402: Control Systems in Biomedical Engineering
Mathematical analysis of dynamic and linear feedback control systems. Emphasis on application to physiological systems, physiological transport, pharmacokinetics, glucose/insulin control, and respiratory control. Performance criteria. Root locus, Nyquist, and other stability criteria. State space analysis with state variable feedback control. Design and compensation. Cannot be taken for credit in addition to ENG EC402. 4 cr - ENG BE 419: Principles of Continuum Mechanics and Transport
This is an introductory course that presents the subjects of solid mechanics, fluid mechanics and transport phenomena in a unified form using the conservation principles (laws of physics) and the mathematical framework of vectors, tensors and matrices. The basic concepts of strain, stress, conservation of mass, momenta and energy, constitutive laws, and applications to solid mechanics, fluid mechanics, diffusion processes and heat transfer will be presented. Illustrative examples from engineering and applied sciences will be provided with each topic. The course will prepare students for advanced courses in traditional fields (elasticity, fluid mechanics, viscoelasticity, poroelasticity, rheology, transport phenomena) as well as emerging fields (nanotechnology, biotechnology, computational mechanics). 4 cr - 在
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- ENG BE 435: Transport Phenomena in Living Systems
Biological systems operate at multiple length scales and all scales depend on internal and external transport of molecules, ions, fluids and heat. This course is designed to introduce the fundamentals of biological transport and to apply these fundamentals in understanding physiological processes involving fluid, mass and heat transfer. Students will learn the fundamental conservation principles and constitutive laws that govern heat, mass and momentum transport processes and systems as well as the constitutive properties that are encountered in typical biological problems. Transport is also critical to the development and proper functioning of biological and medical instruments and devices, which will also be discussed. Biomedical examples will include applications in development of the heart-lung machine, estimation of time of death in postmortem cases, burn injuries through hot water, respiratory flow in smokers lungs, etc. 4 cr - 在
- ENG BE 437: Nanometer Scale Processes in Living Systems
The world at the nanometer-scale is full of dynamic phenomena that are vastly different than those encountered at the macro scale. Biological processes that are of particular contemporary interest, such as cell differentiation, are stimulated by the activity and interaction of biomolecules at the nanoscale. Thus, an understanding of the physics and engineering in such systems is a vital component toward overcoming an immense array of challenging problems in the biological and medical sciences. This course focuses on a conceptual and mechanistic understanding of technologies that permit the study of events at the nanometer scale, including scanning probe microscopes (including AFM) and optical methods such as fluorescence microscopy and related techniques (including single particle tracking, and microrheology).. 4 cr - ENG BE 451: Directed Study in Biomedical Engineering
Individual study of a topic in biomedical engineering not covered in a regularly scheduled course. A faculty member must agree to supervise the study before registration. Term paper and/or written examination. Variable cr. - ENG BE 465: Biomedical Engineering Senior Project
Selection of project and project supervisor must be approved by course instructor. Project is in an area of biomedical engineering, such as biomedical instrumentation, biosensors, tissue engineering, biological signal processing, biological modeling and simulation, clinical imaging or informational systems, etc.Projects will be conducted by teams of two or three students, and projects must include significant design experience. Research of background, planning and initial work on senior design project. Guidance in performing and presenting (in written and oral form) a technical project proposal. Skills in proposal writing, oral presentation techniques. Formal proposal must be approved by technical advisor. 2 cr - ENG BE 466: Biomedical Engineering Senior Project
Completion of project in an area of biomedical engineering. Expanded training in technical project presentation techniques. Includes writing of progress reports, abstracts, final reports. Course culminates with an oral presentation at annual Senior Project Conference. Written final report must be approved by the faculty. 4 cr - ENG BE 467: Product Design and Innovation in Biomedical Engineering
This course teaches students the basic project skills, regulatory principles and best practices for developing a commercial medical device. Lectures and case studies are augmented by real world examples combining both an academic and industrial perspective. Subject matter includes problem identification, product conceptualization, and design, and intellectual property, and formal development including design controls, risk management, FDA regulatory requirements and clinical trials. Student teams will apply their acquired course knowledge and their engineering skills to design and develop a conceptual medical device. This is a required co-requisite to BE465 in the fall for BME Seniors. 2 cr - ENG BE 491: Biomedical Measurements I
Laboratory course designed to accomplish four goals: 1) Develop skills for collecting and analyzing biomedical measurements, 2) Learn proper usage of electronic equipment including oscilloscope, function generator, DAQ, 3) Improve oral and written scientific communication skills through lab reports and class term project presentations, and 4) reinforce concepts presented in BE401, including Fourier Analysis, sampling theory, and filtering, with hand-on experiments. 2 cr - ENG BE 492: Biomedical Measurements II
Laboratory course designed to develop basic instrumentation and analysis skills for physiological and biological measurements. Emphasis will be placed on techniques involving light (spectroscopy and microscopy) and sound (ultrasound). Labs will be focused on data acquisition. Written lab reports will involve quantitative data analysis and interpretation. 2 cr - ENG BE 500: Special Topics in Biomedical Engineering
Coverage of a specific topic in biomedical engineering. One topic covered in depth each semester offered. Subject matter varies from year to year. 4 cr - ENG BE 503: Numerical Methods and Modeling in Biomedical Engineering
This course offers an advanced introduction to numerical methods for solving linear and nonlinear differential equations including ordinary differential equations and partial differential equations. Topics include numerical series, error analysis, interpolation, numerical integration and differentiation, Euler & Runge-Kutta methods, finite difference methods, finite element methods, and moving boundary problems. This course requires knowledge of multivariable calculus, linear algebra, and differential equations. Some knowledge in one computer programming language, such as MATLAB, is required. 4.0 cr - ENG BE 504: Polymers and Soft Materials
An introduction to soft matter for students with background in materials science, chemistry and physics. This course covers general aspects of structure, properties, and performance polymers, polymer solutions and gels. Emphasis is on chain behavior, local chemical interactions and mechanical behavior across multiple size scales. Topics include methods and kinetics of material synthesis, formation assembly, and phase behavior; models of polymer mechanical behavior; techniques for characterizing the structure, phase and dynamics of soft materials; application of soft materials in biotechnology and nanotechnology. Meets with ENG ME 504, ENG MS 504 and PY 744; students may not receive credit for both. 4 cr - ENG BE 505: Molecular Bioengineering I
Provides engineering perspectives on the building blocks of living cells and materials for biotechnology. Focuses on origins and synthesis in life and the laboratory, including biological pathways for sythesis of DNA, RNA and proteins; transduction, transmission, storage and retrieval of biological informatin by macromoleclues; polyerase chain reaction, restriction enzymes, DNA sequencing; energetics of protein folding and trafficking; mechanisms of enzymatic catalysts and receptor-ligand binding; cooperative proteins, multi-protein complexes and control of metabolic pathways; generation, storage, transmission and release of biomolecular energy; and methods for study and manipulation of molecules which will include isolation, purification, detection, chemical characterization, imaging and visualization of structure. 4 cr
